Home SVEDBERG DCDT+ SEDNTERP kDalton XLGraph Download Installation Help

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DCDT+ -related files:

bulletinstallation/update file for version 2.5.1 dated 09/26/2019 [dcdtinst.exe, 5.8 MB, MD5 checksum = a02102d671736fb7a843c64f6069fc22]
bulletNote: you may have to right-click and select 'Save Target As..." to force your browser to save the file to disk instead of trying to display it. If your security settings prevent downloading the installation executable file, you can try downloading this .zip archive, dcdt+_install_exe.zip instead, which just packages that executable file.
bulletThis new version requires the Microsoft .NET framework version 3.5. That software component is usually already present on computers running Windows 10, but it may need to be activated (see below). For Windows XP, Vista, 7 or 8  you will likely need to install .NET framework 3.5. If so, the program installer should detect this and try to open a Microsoft web page from which you can download and install it before the installation continues, but it may give an error message instead. If so, there is a local copy of the .NET 3.5 installation package here.
bulletHow to activate .NET 3.5 in Windows 10: Open Settings and click on 'Apps'. On the right side click on 'Programs and features' under the 'Related settings' heading (you may need to maximize the Settings window in order to see this item). This will bring up a new Control Panel window with a list of installed programs. On the left side of that list click on the 'Turn Windows features on or off' item. This will bring up yet another dialog box with a list of optional Windows features. Near the top of that list is the '.NET Framework 3.5 (includes .NET 2.0 and 3.0) item. If needed, check the check box for that item, and then click 'OK'. Your computer may then need to download additional files from the Microsoft web site to activate .NET 3.5 (it will do this automatically if needed).
bulletHow to activate .NET 3.5 in Windows 11: Open Settings and click on 'Apps'. In the middle of the list click on 'Optional Features'. Then scroll down until you see 'Related settings' and then click on 'More Windows features'. This will bring up a new dialog box with a list of optional Windows features. Near the top of that list is the '.NET Framework 3.5 (includes .NET 2.0 and 3.0) item. If the box to the left of the folder icon on that line of the list is empty (white) then check that empty box (which will then turn a solid color), and then click 'OK'. Your computer may then need to download additional files from the Microsoft web site to activate .NET 3.5 (it will do this automatically if needed).
bulletIf you encounter any installation issues please see Installation Help
bulletFor differences from the original version (1.00), see the revision history
bulletIf you encounter any installation issues please see Installation Help
bulletFor differences from the original release (6.10), see the revision history
bulletThe DCDT+ source code is also now available on the RASMB software depot (link here), and may be freely modified, used, and distributed under the terms of the GNU General Public License version 3.
bulletPrintable PDF User Manual (same information as the Help file, but formatted for printing and with a Table of Contents and index giving the page numbers, 9.8 MB)
bulletPreprint of Analytical Biochemistry 412, 189-202 (2011) article comparing g(s*) and PBM fitting approaches (sorry, available by e-mail request only)
bulletSupplementary material for the above article (discusses when is the concentration high enough to allow a reversible oligomer to be treated as a non-dissociable species?)
bulletReprint of Analytical Biochemistry 354, 238-246 (2006) article describing new fitting algorithms implemented in version 2 (PDF, 817 KB)

SVEDBERG-related files:

Installation/update file for version 7.1.2 dated 07/08/2022 [svedinst.exe, 9.2 MB, MD5 checksum = 3667c33062db56921477b54ffff5f37c]

bulletNote: you may have to right-click and select 'Save Target As..." to force your browser to save the file to disk instead of trying to display it. If your security settings prevent downloading the installation executable file, you can try downloading this .zip archive, svedberg_install_exe.zip instead, which just packages that executable file.
bulletThis new version requires the Microsoft .NET framework version 3.5. That software component is usually already present on computers running Windows 10 or 11, but it may need to be activated (see below). For Windows XP, Vista, 7 or 8  you will likely need to install .NET framework 3.5. If so, the program installer should detect this and try to open a Microsoft web page from which you can download and install it before the installation continues, but it may give an error message instead. If so, there is a local copy of the .NET 3.5 installation package here.
bulletHow to activate .NET 3.5 in Windows 10: Open Settings and click on 'Apps'. On the right side click on 'Programs and features' under the 'Related settings' heading (you may need to maximize the Settings window in order to see this item). This will bring up a new Control Panel window with a list of installed programs. On the left side of that list click on the 'Turn Windows features on or off' item. This will bring up yet another dialog box with a list of optional Windows features. Near the top of that list is the '.NET Framework 3.5 (includes .NET 2.0 and 3.0) item. If needed, check the check box for that item, and then click 'OK'. Your computer may then need to download additional files from the Microsoft web site to activate .NET 3.5 (it will do this automatically if needed).
bulletHow to activate .NET 3.5 in Windows 11: Open Settings and click on 'Apps'. In the middle of the list click on 'Optional Features'. Then scroll down until you see 'Related settings' and then click on 'More Windows features'. This will bring up a new dialog box with a list of optional Windows features. Near the top of that list is the '.NET Framework 3.5 (includes .NET 2.0 and 3.0) item. If the box to the left of the folder icon on that line of the list is empty (white) then check that empty box (which will then turn a solid color), and then click 'OK'. Your computer may then need to download additional files from the Microsoft web site to activate .NET 3.5 (it will do this automatically if needed).
bulletIf you encounter any installation issues please see Installation Help
bulletFor differences from the original release (6.10), see the revision history
bulletThe SVEDBERG source code is also now available on the RASMB software depot (link here), and may be freely modified, used, and distributed under the terms of the GNU General Public License version 3.
bulletPrintable PDF User Manual (same information as the Help file, but formatted for printing and with a Table of Contents and index giving the page numbers, 5.4 MB)
bullet 1994 book article in PDF format (requires Adobe Acrobat Reader) (467 KB) 
bullet 1997 Biophysical Journal article in PDF format (requires Adobe Acrobat Reader) (305 KB)

KDALTON-related files:

installation file for KDALTON version 4.0.0 dated 04/21/2020 (5.7 MB)

bulletAfter downloading, just run this self-extracting archive to expand the files and start the installation program
bulletDuring installation you may get warning messages that the installer is trying to install support libraries that are older than ones with the same name already installed on your computer. This is not a problem. Simply accept the default behavior to keep the newer version. Similarly, if you see messages about "access violation" or "registration" errors, simply push the 'Ignore' button and let the installer proceed.

SEDNTERP-related files:

SEDNTERP version 3.0.4 installation file (program dated 06/05/2022 (10,014,720 bytes, MD5 checksum = 6D1C4F302CE31A3E40DC0686CBC12D6A). This version will run under Windows 11 (or older versions of Windows back to Windows Vista).  The start-up database file, sednterp3.db, will be installed along with the program, but if you need another copy (for example, to put a copy into a shared folder so everyone in the lab can share a single database) it can be downloaded as a .zip archive via this link (44,782 bytes, MD5 checksum = 977C46E811FA6C6EB06D16FDC5FF1416).

The beta version of SEDNTERP 2 is no longer downloadable from the Biomolecular Interaction Technologies Center (BITC) website at the University of New Hampshire, but you can download a copy from this web site here

SEDNTERP version 3 installation notes:

bulletThis SEDNTERP version requires prior installation of version 4.0 (or higher) of the Microsoft .NET framework, which in turn means it will not run under Windows XP.  Version 4.x of the .NET framework will always be present under Windows 8, 10, or 11, but might not be installed for Windows 7 or Vista.  If the needed version of .NET is not present when you run the SEDNTERP 3 installer, it should try to download and install it from the Microsoft website.
bulletThis version uses a new database structure, but it can import databases created either by versions 1.00-1.09 or UNH SEDNTERP version 2.
bulletAlthough by default SEDNTERP will be installed for all users on a computer, each user will have their own database and set of defaults (preferences). 
bulletIn order for multiple users to share the same database, put a copy of the database file (sednterp3.db) into a shared folder (which can be a network folder), and then open that file after the program starts and say 'yes' when it asks whether to set that shared file as the default database.
bulletStarting with version 3.03, for new installations the database file will be placed into the program folder (because that is the only location that works for all computer configurations). Unfortunately that location may mean that the database file (which contains the information you add about your samples, buffers, and experiments) might not be backed up by your backup software.  Therefore when the program runs the first time you will be asked whether you wish to move the database to some location where it will definitely be backed up (and for which you have read/write file access privileges), such as your Documents folder.
bulletYou will need Administrator privileges to install SEDNTERP.

The SEDNTERP version 1 source code is also now available on the RASMB software depot (link here), and the version 3 source code will be available there in the near future. The source code  may be freely modified, used, and distributed under the terms of the GNU General Public License version 3.

XLGraph-related files:

XLGraph_install.exe,  full installation of version 4.0.0 dated 04/26/2020 [4.1 MB]

bulletThis 32-bit version does run under Windows 10
bulletAfter downloading, just run this self-extracting archive to expand the files and start the installation program
bulletDuring installation you may get warning messages that the installer is trying to install support libraries that are older than ones with the same name already installed on your computer. This is not a problem. Simply accept the default behavior to keep the newer version. Similarly, if you see messages about "access violation" or "registration" errors, simply push the 'Ignore' button and let the installer proceed.